This program is a self-contained product for preparation of formal paternity reports with many allied facilities. It works very naturally with DNA·VIEW for DNA types and also deals thoroughly with classical blood groups.
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Long Island Laboratories (800)551-1111 Tested Man: Reverend Mr. Dimmesdale (C) 1000-00036 Mother: Hester Prynne (C) 1000-00034 Child: Pearl 1000-00035 SUMMARY OF FINDINGS: Reverend Mr. Dimmesdale is not excluded as the father of Pearl. Combined paternity index = 27000000 Probability of paternity = 99.999996% (50% prior probability) T E S T OBSERVED PHENOTYPES CALCULATION OF PATERNITY INDEX Tested Paternity Nonpaternity Ratio Mother Child Man Assumed (X) Assumed (Y) (X/Y) PCR loci D8S1179 12 14 12 15 14 15 0.25 0.101 2.47 D21S11 30 30 30.2 29 30.2 0.5 0.0154 32.5 D7S820 8 12 12 12 0.5 0.0545 9.17 CSF1PO 12 12 14 10 14 0.5 0.0112 44.7 D3S1358 15 17 15 15 17 0.25 0.153 1.63 TH01 8 8 8 9.3 0.5 0.208 2.4 D13S317 12 11 12 11 1 0.246 4.06 D16S539 9 11 9 11 9 11 0.5 0.254 1.97 TPOX 8 8 8 1 0.362 2.76 D18S51 14 17 16 17 12 16 0.25 0.0832 3 D5S818 11 13 11 12 12 13 0.25 0.183 1.37 FGA 25 22 25 22 24 0.5 0.217 2.31 |
Tested man: (C) Eltinge, JulianWho? 24-9876 Case 171 Mother: (C) Herbert, Mathilda 24-1010 March 3, 1997 10:36 Child: Bicious, Biddney 24-9988SUMMARY: Exclusion Hp 6-PGD FILING CODES: F RIV rE fH mH - t13 (PATER ver 3.1.1) Excluding systems with an inconsistency -- Paternity Index = 572; Probability of paternity = 0.998 (at 50% prior); Probability of Exclusion (given mother and child) = 99.9925% T E S T OBSERVED PHENOTYPES CALCULATION OF PATERNITY INDEX Tested Paternity Nonpaternity Ratio Random Man Mother Child Man Assumed (X) Assumed (Y) (X/Y) Eligible Red Cell Antigens ABO A1 A2 A 0.0813 0.0556 1.464 1 Rh DCcE DCcE DCcEe 0.2481 0.0778 3.19 0.2891 MNSs N MN M 1 0.562 1.779 0.808 Duffy a+b- a+b+ a+b+ 0.479 0.557 0.861 0.824 Serum Proteins Gc 1f-2 1f-2 1s-1f 0.25 0.215 1.163 0.675 Hp 2 2 1 Inconsistent 0.577 0.821 Red Cell Enzymes AcP AC BC AB 0.25 0.3057 0.818 0.849 6-PGD A A C Inconsistent 0.982 1 ADA 2-1 2-1 2-1 0.5 0.5 1.001 1 PGM 1- 1- 1 0.1905 0.144 1.323 0.942 HLA A locus 2,11 2,11 2,32 0.01395 0.00457 3.053 0.0666 B locus 14,21 14,21 14,40 DNA Probes (bp) pS194/D7S104 5740 5740 5740 0.5 0.1766 2.831 0.322 Pst I 6990 6990 6990 TBQ7/D10S28 1230 1230 1780 0.25 0.034 7.35 0.0337 Hae III 950 1450 1450 The HLA recombination rate is taken as 0.01. However, using 0 recombination in HLA X/Y=2.911 and P{C|M,M}=0.5. B21=(21,49,W50) B40=(40,W41,W47,W48,W60,W61) cc: John J Fitzmorton Patricia M. Cavenaugh Office of the District Attorney 1422 N. Hampshire St. Walden, Ohio Walden, Ohio Effect of prior probability on the likelihood of paternity: prior probability (%) 10 20 30 40 50 60 70 80 90 likelihood of paternity (%) 98.5 99.3 99.6 99.7 99.8 99.9 99.93 99.96 99.98 Avuncular and Incest Indices Degree (0=alleged father or parthenogenesis, 1=uncle, etc.) of relation 0 1 2 3 4 Paternal 0 15.44 6.87 3.2 1.913 Maternal 0 39.3 51.5 25.39 11.16 On the basis of the genetic observations listed above (that are consistent with paternity) Julian Eltinge would be 572 times as likely to father Biddney Bicious as would a random man of similar ethnic background. |
ABO Frequency tables in use 1991/3/20 11:20 | ||||
Caucasian | Hispanic | Black | Asian | |
O | 0.664 | 0.812 | 0.707 | 0.584 |
B | 0.074 | 0.056 | 0.127 | 0.171 |
A2 | 0.066 | 0.021 | 0.041 | 0.006 |
A1 | 0.196 | 0.111 | 0.125 | 0.239 |
DETAIL calculation worksheet ****** ABO |
ABO Computation of X=P{C|M,tested man is father} = 0.05116 Mother: A1 Child: A2 Tested man: A Paternal genes A2 A1 O A2 A1 Sperm= O O A2 A2 A2 Pat frequency= 0.0736 0.3888 0.0736 0.0019 0.0101 Maternal genotype Likelihood of A2 phenotype: Ovum M freq A1 O 0.4362 0.0321 0.0008 0.0044 A1 A2 0.0253 0.0019 0.0098 0.0019 0.0003 |
ABO Computation of Y=P{C|M,random man} = 0.01754 Mother: A1 Child: A2 Paternal genes Sperm= O A2 B A1 Pat frequency= 0.5840 0.0060 Maternal genotype Likelihood of A2 phenotype: Ovum M freq A1 A2 0.0253 0.0148 0.0002 A1 O 0.4362 0.0026 |